4 Duodenal Ulcer, Causes, Symptoms and How to Overcome

Duodenal ulcer, causes, symptoms and how to overcome. What is Duodenal Ulcer ? Duodenal ulcer is defined as a well-circumscribed mucosal or submucosal defect that can penetrate the mucosal layer of the mucosa to the serous layer to cause perforation. Gastric ulcer is a round or oval picture with a size of more than 5 millimeters from the submucosal depth of the gastric mucosa due to interruption of gastric mucosal integrity with ulcer base covered with debris.


4 Duodenal Ulcer, Causes, Symptoms and How to Overcome
Duodenal Ulcer
By definition, peptic ulcer is damage or loss of mucosal tissue to the lamina propria in various digestive tracts of food which are exposed to gastric acid fluid, namely esophagus, stomach, duodenum, and after the gastroenterostomy also jejunum. However, this disease occurs mainly in the duodenum and stomach, resulting in acute or chronic gastritis. With the discovery of H. Pylori bacteria in gastrointestinal disorders, currently considered H. Pylori is a major cause of gastric ulcer.

Duodenal ulcer, causes, symptoms and How to Overcome

Therefore, peptic ulcer is an ulcer that occurs in the submucosa, mucosa and sometimes to the muscular layer of the gastrointestinal tract which is always associated with stomach acid which contains enough HCL. These include ulcer ulcers found at the bottom of the upper oesophagus, stomach and duodenum. It may also be found in ulcers in the yeyenum, namely patients who experience gastroyeyenostomy.

Duodenal ulcer, the most common type of peptic ulcer, occurs in the duodenum, which is the first few centimeters of the small intestine, just below the stomach. Pain in the pit of the stomach is a typical sign of this disease and these symptoms are often heard. The stomach as a food reservoir serves to receive food and empty food into the duodenum. Because it is often associated with all types of food, the stomach will experience chronic irritation and become ulcer or ulcer.

Gastric ulcers spread throughout the world with different prevalences depending on social, economic, and demographic, found more in men with an increased incidence in the elderly and low socioeconomic groups. Clinically, duodenal ulcer is more common than gastric ulcer. In some countries like Japan there are more gastric ulcers than duodenal ulcers. Gastric ulcers are larger and more prominent so that at autopsy examination is more frequent or easier than duodenal ulcer

In the UK around 6-20% of the population suffer from ulcers at the age of 55 years, while the prevalence is 2-4%. In the United States there are 4 million patients with pepsin acid disorder, the prevalence is 12% in men and 10% in women.

The most age is between the ages of 45-65 years with a tendency to get older, the prevalence is increasing with male dominated more than women. From time to time, management of gastric ulcers is better along with the discovery of causative factors that are supported by advances in the health sector that have managed to find and develop treatments that have the potential to overcome gastric ulcers.

Signs and Symptoms of Duodenal Ulcer

Signs or symptoms of ulcer can disappear for several days, weeks or months. It can even disappear and come back, often without identifiable causes. Many individuals experience ulcer symptoms and 20-30% experience perforation or hemorrhage without any prior manifestations. Here are some of the symptoms of Doudenum ulcer including:

1. Pain
Usually patients with ulcers complain of pain, such as a burning sensation in the middle epigastrium or in the back. It is believed that pain occurs when the stomach and duodenal acid levels increase. Other theories suggest that contact with lesions with acid which is a reflexlocal mechanism that starts the contraction of the surrounding smooth muscles. Pain usually goes away by eating, because eating neutralizes acid, but if the stomach is empty, it will reappear.

2. Vomiting:
Vomiting can be a symptom of peptic ulcer. This is associated with the formation of scar tissue or acute swelling of mucous membranes that have surrounding inflammation in acute ulcers. Vomiting can occur or is not preceded by nausea, usually after severe pain which is removed by ejection of the stomach acid content.

3. Constipation and bleeding
Constipation can occur in ulcer patients, possibly as a result of diet. Patients can also present with gastrointestinal bleeding, a small proportion of patients who experience previous acute ulcers have no complaints, but they show symptoms afterwards.

Causes of Duodenal Ulcer

There are several causes of duodenal ulcers including:

1. Infection of H. Pylori bacteria
In the past five years, found at least 75% of peptic ulcer patients suffer from chronic infection at the end of the gastric mucosa, and the duodenal mucosa by H. pylori bacteria. Once the patient is infected, the infection can last a lifetime unless the germs have been eradicated. Furthermore, bacteria are able to perform mucosal barrier penetration, both with their own physical ability to penetrate the barrier and by releasing digestive enzymes that dilute the barrier. As a result, strong digestive acid secretions secreted by the stomach can penetrate into the epithelium tissue and digest the epithelium, even the surrounding tissue. This situation leads to the condition of peptic ulcer.

2. Increased acid secretion
In most people who suffer from peptic ulcer in the early part of the duodenum, the amount of gastric acid secretion is greater than normal, often even twice as normal. Predisposition to increased acid secretion is a psychogenic factor such as when experiencing depression or anxiety.

3. Drrugg consumption
Drrugg, like NSAIDs, has the inhibitory effect of cyclo oxygenase which inhibits systemic prostaglandin synthesis from arachidonic acid, including the gastric and duodenal epithelium. On the other hand, this also decreases HCO3 so that it weakens mucosal protection. Another effect is to damage the local mucosa through nonionic diffusion into mucosal cells. and this also has an impact on platelet aggregation so that it increases the danger of bleeding in the ulcer.

4. Reflux of gastric intestines
Reflux of gastric intestines with abundant bile salts and pancreatic enzymes that meet the mucosal surface can predispose to mucosal epithelial damage.

How to Overcome of Duodenal Ulcer
In how to deal with duodenal ulcer can be done after knowing the cause and severity. Keep in mind that there are a number of causes of duodenal ulcer. Therefore, the doctor will make a diagnosis first to find out what causes the doudenum ulcer to appear.

Thus reviews of duodenal ulcer, causes, symptoms and how to overcome. In this paper, the aim is to make the reader know more about doudenum ulcer, and thank you for reading.

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